Kopp, K., J. Z. Gasiorowski, D. Chen, R. Gilmore, D. Leary, J. Norton, E. Chan, D. A. Dean and S. Huang. 2007. Pol I transcription and pre-rRNA processing are coordinated in a transcription dependent manner in mammalian cells. Mol Biol Cell 18:394-403 (view .pdf file)
Mutlu, G. M., D. Green, A. Bellmeyer, C. M. Baker, Z. Burgess, J. W. Christman, N. Foiles, D. W. Kamp, A. J. Ghio, N. S. Chandel, D. A. Dean, J. I. Sznajder, and G. R. S. Budinger. 2007. Ambient particulate matter accelerates coagulation via an IL-6 dependent pathway. J. Clin. Invest. 117:2952-2961. (view .pdf file)
Zhou, R., and D. A. Dean. 2007. Gene transfer of IL-10 to the murine cornea using electroporation. Exp Med Biol (in press)
Bellmeyer, A. J. M. Martino, N. S. Chandel, G. R. S. Budinger, D. A. Dean, and G. M. Mutlu. 2006. Leptin Resistance Protects Mice from Acute Lung Injury. Am J Respir Crit Care Med 175:587-94. (view .pdf file)
Gasiorowski, J. Z., and D. A. Dean. 2006. Intranuclear trafficking of episomal DNA is transcription dependent. Mol Therapy 15: 2132-2139. (view .pdf file)
Geiger, R. C., W. Taylor, M.R. Glucksberg, and D.A. Dean. 2006. Cyclic stretch-induced reorganization of the cytoskeleton and its role in enhanced gene transfer. Gene Therapy (view .pdf file)
E. Hillery, F.M. Munkonge, S. Xenariou, D.A. Dean, and E.W.F.W. Alton 2006. Non-disruptive, Sequence-Specific Coupling of Fluorochromes to Plasmid DNA. Analytical Biochem 352:169–175. (view .pdf file)
Mutlu, G. M., D. A. Machado-Aranda, J. E. Norton, A. Bellmeyer, and D. A. Dean. 2006. Electroporation-mediated gene transfer of the Na+,K+-ATPase both protects from and rescues LPS-induced acute lung injury in mice. Am J Respir Crit Care Med 176:582-590. (view .pdf file)
Vaughan, E. E., J. V. DeGiulio, and D. A. Dean. 2006. Intracellular trafficking of plasmids and viral vectors. Curr Gene Ther 6:671-81
Vaughan, E. E., and D. A. Dean. 2006. Intracellular trafficking of plasmids during transfection is mediated by microtubules. Mol Therapy 13:422-428. (view .pdf file)
Zhou, R., and D. A. Dean. 2006. Gene transfer of IL-10 to the murine cornea using electroporation. Exp Med Biol 232:362-369. (view .pdf file)
Zhou, R., J. E. Norton, N. Zhang, and D. A. Dean. 2006. Electroporation-mediated transfer plasmids to the lung results in reduced TLR9 signaling and inflammation. Gene Therapy 14:775-780. (view .pdf file)
Dean, D. A., D. D. Strong, and W. E. Zimmer. 2005. Nuclear Entry of Non-Viral Vectors. Gene Therapy 12:881-890, invited review. (view .pdf file)
Dean, D. A. 2005. Non-viral Gene Transfer to Skeletal, Smooth, and Cardiac Muscle in Living Animals. Am. J. Physiol, Cell Physiol 289:C233-245, invited review. (view .pdf file)
Gasiorowski, J. Z., and D. A. Dean. 2005. Post-mitotic nuclear retention of episomal plasmids is altered by DNA labeling and detection methods. Mol. Therapy 12:460-467. (view .pdf file)
Jones, J. C. R., K. Lane1, E. Lecuona, R.C. Geiger, D. A. Dean, E. Correa-Meyer, M. Gonzales, Kevin Campbell, J.I. Sznajder and G. R. S. Budinger. 2005. Laminin-6 assembles into Multimolecular fibrillar complexes with perlecan and participates in mechanosignal transduction via a dystroglycan-dependent, integrin-independent, mechanism. J Cell Science 118:2557-2566. (view .pdf file)
Machado-Aranda, D., Y. Adir, J. L. Young, A. V. Yeldandi, G. R. S. Budinger, J. I. Sznajder, and D. A. Dean. 2005. Non-viral gene transfer of the Na+,K+-ATPase b1 subunit using electroporation increases lung liquid clearance in rats. Am. J. Respir. Crit. Care Med. 171:204-211. (view .pdf file)
Zhou, R., R. C. Geiger, and D. A. Dean. 2004. Intracellular Trafficking of Nucleic Acids. Expert Opinion Drug Delivery 1:127-140.
(view .pdf file)
Wang, L, D. A. Dean, and R. C. MacDonald. 2004. Effect of Vinblastine on Transfection: Influence of Cell Types, Cationic Lipids and Promoters. Cur Drug Delivery 2:93-96. (view .pdf file)
Zhang, G., G. Gao, Y. K. Song, R. Vollmer, D. B. Stolz, J. Z. Gasiorowski, D. A. Dean, and D. Liu. 2003. Hydroporation as the Mechanism of Hydrodynamic Delivery. Gene Therapy11:675-682. (view .pdf file)
Dean, D. A. 2003. Electroporation of the vasculature and the lung. DNA Cell Biol 22:797-806 (view .pdf file)
Nunamaker, E. A., H. Zhang, Y. Shirasawa, J. N. Benoit, and D. A. Dean. 2003. Electroporation mediated delivery of catalytic oligodeoxynucleotides for manipulation of vascular gene expression. Am. J. Physiol. 285: H2240-H2247 (view .pdf file)
Dean, D. A.,
D. Machado-Aranda, K. Blair-Parks, A. V. Yeldandi, and J. L.
Young. 2003. Electroporation
as a method for high-level non-viral gene transfer to the lung. Gene Therapy
10: 1608-1615 (view .pdf file)
Young, J. L., J. N. Benoit and D.
A. Dean.
2003. Effect
of a DNA nuclear targeting sequence on gene transfer and expression
of plasmids in the intact vasculature. Gene Therapy
10: 1465-1470. (view .pdf file)
Gasiorowski, J., and D.
A. Dean. 2003. Mechanisms
of nuclear transport and interventions. Adv. Drug
Deliv. Rev. 55: 703-716. (view .pdf file)
Munkonge, F. M., D. A. Dean,
E. Hillery, U. Griesenbach. & E.W.F.W
Alton. 2003. Emerging
significance of DNA nuclear import in gene therapy. Adv. Drug Deliv. Rev. 55: 749-760. (view .pdf file)
Dean, D. A. 2003. Nuclear
transport: an emerging opportunity for drug delivery. Adv. Drug Deliv. Rev.
55: 699-702. (view .pdf file)
Taylor, W., K. E. Gokay, C. Capaccio, E. Davis, M. R. Glucksberg,
and D. A.
Dean. 2003. Effects
of cyclic stretch on gene transfer in alveolar epithelial cells. Mol Therapy 7:542-549. (view .pdf
file)
Shirasawa, Y., T. J. Rutland, J. L. Young, D.
A. Dean, and J.
N. Benoit. 2003. Modulation
of protein kinase c (PKC)-mediated contraction
and the possible role of PKCepsilon in rat mesenteric arteries.
Frontiers Bioscience 8:133-138. (view .pdf file)
Fillmore, R. A., D. A. Dean, and
W. E. Zimmer. 2002. SRF
and Nkx 3.1-regulated expression of the smooth muscle gamma actin
mRNA
within prostate epithelial cells. Gene Expression 10:201-211. (view
.pdf file)
Budinger,
G. R. S., M. Tso, D. S. McClintock, D. A. Dean, J.
I. Sznajder, and N. S. Chandel. 2002. Hyperoxia
induced apoptosis does not require mitichondrial reactive oxygen
species and is
regulated by Bcl-2 proteins. J. Biol. Chem 277: 15654-60. (view .pdf file)
Hirschi, K. K., N. S. Belaguli, D.
A. Dean,
R. J. Schwartz, and W. E. Zimmer. 2002. TGF-
induction of smooth muscle phenotype
requires transcriptional and translational control of serum response
factor. J. Biol. Chem 277: 6287-6295. (view
.pdf file)
Young, J. L., and D. A. Dean. 2002.
Nonviral
gene transfer strategies for the vasculature. Microcirculation
9:35-50. (view .pdf file)
Blair-Parks, K., B. C. Weston, and D.
A. Dean. 2002. High
level gene transfer for the cornea using electroporation.
J. Gene Med 4: 92-100. (view
.pdf file)
Dean, D. A., G. Urban, I. V. Aragon,
M. Swingle, S. Rusconi, M. Bueno, B. Miller, N. M. Dean, and
R. E. Honkanen. 2001. Serine
/ Threonine Protein Phosphatase 5 (PP5) Participates in the Regulation
of Glucocorticoid Receptor Nucleocytoplasmic Shuttling. BioMed
Central 2: 6-14. (view .pdf file)
Li, S, F. C. MacLaughlin, J. G. Fewell, M. Gondo, J. Wang, J.
L. Nordstrom, D. A. Dean, E.
Hanna, and . C. Smith. 2001.Muscle-specific
enhancement of gene expression by incorporation of SV40
enhancer in the expression plasmid. Gene Therapy 8: 494-497. (view
.pdf file)
Dean, D. A., and R. A. Perkin.
2001.
Gene
therapy: if at first you don't succeed… Am. Fam. Physician
63: 707-713. (view .pdf file)
Norwood, N., T. M. Moore, D. A. Dean,
R. Bahattacharjee, M. Li, and T. Stevens. 2000. Store-operated
calcium entry and increased
endothelial cell permeability. Am. J. Physiol. Lung Cell Mol.
Physiol. 279: L815-24. (view .pdf file)
Dean, D. A. 2000. Peptide
nucleic acids: versatile tools for gene therapy strategies.
Adv. Drug Delivery Rev. 44: 81-95. (view
.pdf file)
Martin, J. B., J. L. Young, J. N. Benoit, and D.
A. Dean. 2000.
Gene
transfer to intact mesenteric arteries by electroporation.
J. Vasc. Res. 37: 372-380. (view .pdf file)
Bustamante, J. O., E.R. Michelette, J.P. Geibel, J.A. Hanover,
T.J. McDonnell, and D. A. Dean.
2000.
Dendrimer-assisted patch-clamp sizing
of nuclear pores. Pflügers
Archiv. Eur. J. Physiol. 439: 838-844. (view
.pdf file)
Bustamante, J. O., E.R.F. Michelette, J.P. Geibel, D.
A. Dean,
J.A. Hanover, and T.J. McDonnell. 2000. Calcium,
ATP, and nuclear pore channel gating. Pflügers Archiv. Eur. J. Physiol. 439:
433-444. (view .pdf file)
Dean, D. A., B. S. Dean, S.
Muller, and L. C. Smith. 1999. Sequence
requirements for plasmid nuclear
import.. Exp. Cell Res. 253: 713-722. (view
.pdf file)
Reddy, J. A., D. A. Dean, M. D. Kennedy,
and P. S. Low. 1999. Influence of
polycations on targeted anionic-liposome mediated
gene delivery and expression. J. Pharm. Sci. 88: 1112-1118. (view
.pdf file)
Wang, G., X. Xu, B. Pace, D. A. Dean,
P. M. Glazer, P. Chan, S. R. Goodman, and I. Shoklenko. 1999. Peptide
nucleic acid (PNA) binding-mediated induction of human gamma-globin
gene expression.
Nucleic Acids Res. 27: 2806-2813. (view
.pdf file)
Wilson, G. L., G. Wang, B. S. Dean, and D.
A. Dean. 1999. Nuclear
import of plasmid DNA in digitonin -permeabilized cells requires
both cytoplasmic factors and specific DNA sequences. J. Biol.
Chem. 274: 22025-22032. (view
.pdf file)
Dean, D. A., J. N. Byrd, Jr.,
and B. S. Dean. 1999. Nuclear
targeting of plasmid DNA in human corneal cells. Cur. Eye
Res., 19: 66-75.( view .pdf file)
Vacik, J., B. S. Dean, W. E. Zimmer, and D.
A. Dean. 1999. Cell-specific
nuclear import of plasmid DNA. Gene
Therapy, 6: 1006-1014. (view
.pdf file)
Tran, M. T., D. A. Dean, R.
N. Lausch, and J. E. Oakes. 1998. Membranes
of herpes simplex virus type-1-infected human corneal epithelial
cells are not
permeabilized to macromolecules and therefore do not release
IL-1alpha. Virology 244: 74-78. (view
.pdf file)
Dean, D. A. 1997. Import
of plasmid DNA into the nucleus is sequence-specific. Exp.
Cell Res. 230:
293-302. (view
.pdf file) |